Endocrine Abstracts

Introduction: Non-functioning pituitary adenomas are relatively common. A large number of these tumors are asintomathic pituitary microadenomas, that are increasingly detected because of sensitive imaging techniques improves. Those tumors that require treatment are generally macroadenomas and come to medical attention because of mass effect (visual field defects, headache, …) and/or hypopituitarism.Objective: To assess non-functioning pituitary ade...

Introduction: Hypophysary aneurysms are rare, they account for 1% to 2% of all intracranial aneurysms (1) and can be mistaken for pituitary adenomas, since they can have similar symptoms and even radiological signs especially if it’s an aneurysm completely thrombosed as angiography will show only avascular mass (2).Clinical case: A 84 year old female with past medical history of hypertension, dyslipidemia and depressive disorder, presents to emergen...

Introduction: Papillary thyroid cancer (PTC) has an excellent prognosis in most cases with a 10-year survival rate of more than 95% but decreases drastically in cases of PTC iodine-refractory, in recurrent and/or metastatic disease. Tyrosine kinase inhibitors, such as lenvatinib or sorafenib, have been approved in such cases and in some cases are able to stabilize the disease and prolong survival. However, serious side effects have been reported such as fistula formation, blee...

Introduction: Many studies have shown that cigarette smoking exerts multiple effects on the thyroid gland. Smoking seems to induce changes in thyroid function tests, like a left-shift in serum TSH level that is more apparent in iodine-deficient subjects and increase in thyroid hormones. We describe the effect of an intensive thyroxine intravenous treatment in severe hypothyroid patients and the results depending on their smoking status.Material and metho...

Aim: To establish the effect of a supplement containing 250 mg red yeast rice extract, 525 mg berberine and 50 mg coenzyme Q10 on insulin sensitivity in patients with hypercholesterolemia and prediabetes.Methods: For this open, uncontrolled study, patients of age 30–75 years, with hypercholesterolemia (LDL cholesterol >130 mg/dl and triglycerides <300 mg/dl), and prediabetes without overt cardiovascular disease, untreated in the previous 6 m...

Introduction: Pituitary adenomas are considered to be benign tumors that are diagnosed by its sympthoms (secondary to compression or hormonal secretion) or incidentally in an imaging technique performed because of another reason. ‘Silent’ somatotrophinomas are very rare. This type of adenoma is typically large and despite it presents with mild or no acromegalic features it usually develops hormone secretion.A case report: A 29-year-old spanish ...

Clinical case: A 19-year-old male came to the Emergency Department complaining about a holocraneal nonpulsatile headache growing in intensity for the last 3 h, unresponsive to common analgesics. He had been suffering anxiety sleep deprivation, nervousness, tremor and heart palpitations for the last week. Family history was irrelevant, and the patient had no history of hypertension, dyslipidaemia, diabetes or smoking or medication use; he reported moderate alcohol, coffee and e...

A 27-year-old male without relevant familial or personal history had three TIAs in the last year, lasting for about 20 min with partial right palsy and aphasia. By the time he was cared for in the Emergency Department. he had already recovered; his lab tests, chest X-ray and EKG were normal but his BP was high (PAS 170–190 mmHg, PAD 105–120 mmHg). He had no chest pain, headache or neurovegetative symptoms. On discharge the patient was treated with manidipine and ASA ...

Clinical Case: A 39-year-old woman was referred to our Hypertension Clinic for workup after three episodes of TIA with SBP >180 mmHg in the last 6 months. Diagnosed and treated of hypertension and hypokaliemia since she was 15 years old, no secondary cause had been searched. She was treated with Telmisartan/Amlodipine/Hydrochlorothiazide 80/10/25 mg plus Carvedilol 12.5 mg BID and potassium supplements. She had no history of diabetes or dyslipidemia and did not smoke. Heig...

Clinical Case: A hypertensive 60-year-old woman with nephroangiosclerotic stage IV chronic renal failure (eGFR 23.44 ml/min/1.73 m2) was referred to our hypertension clinic after the CT finding of a 26-mm left adrenal mass with adenoma density during hypertension workup, with normal right adrenal. Physical exam was unremarkable except for BP 167/98 mmHg. Plasma aldosterone was 353 ng/ml, PRA 1.3 ng/ml/h, ratio 90.2, K+3.1 mEq/l, and metanephrines were nor...